نبذه عن الكتاب: The discovery of the double-helix structure of DNA by Watson and Crick more than fty years ago was the starting point of a new era in molecular biology. Since then, our knowledge of biological structures and processes has grown tremendously. But many of these advances would have been unthinkable without using computational methods. Computer science plays a leading role in the emerging interdisciplinary eld of bioinformatics. Only the interplay between biological methods and concepts from informatics has enabled us to successfully maintain projects such as the Human Genome Project. But completing this project also initiated further challenges for bioinformatics. The main goal now is to analyze and make use of the collected data. Moreover, new areas are explored, for instance, the prediction of the spatial structure of proteins. These results will be useful for designing new drugs and improved medical therapies; in this context, computer science faces bold challenges. However, progress in molecular biology also in uences the design and development of computer science methods and concepts, as in the exciting research eld of molecular computing.