📘 ❞ Femtomolar bradykinin-induced relaxation of isolated bovine coronary arteries, mediated by endothelium-derived nitric oxide ❝ كتاب
كتب طب بيطرى - 📖 ❞ كتاب Femtomolar bradykinin-induced relaxation of isolated bovine coronary arteries, mediated by endothelium-derived nitric oxide ❝ 📖
█ _ 0 حصريا كتاب Femtomolar bradykinin induced relaxation of isolated bovine coronary arteries, mediated by endothelium derived nitric oxide 2024 oxide: bradykinininduced endotheliumderived من كتب طب بيطرى We reported previously that induces dependent at nanomolar (nM) concentrations in arteries with an intact Recently we have found the presence 10 microM indomethacin, femtomolar (fM) induce some (approximately 10% examined) The present study was designed to characterize fM Relaxation completely abolished repeated application bradykinin, 100 N(omega) nitro L arginine methyl ester and methylene blue nM partly affected these treatments both inhibited a B2 kinin receptor antagonist, [Thi5,8, D Phe7] concentration manner, but not B1 des Arg9, [Leu8] In captopril, angiotensin converting enzyme (ACE) inhibitor, all examined this experiment showed These results show relax response is predominantly release via stimulation endothelial receptors may be on ACE activity مجاناً PDF اونلاين الطب البيطري (بالإنجليزية: Veterinary medicine) أو البيطرة هو تطبيق المبادئ الطبية والتشخيصية والعلاجية الحيوانات الإنتاجية والمنزلية والبرية يحتوي هذا القسم علي العديد الكتب المتميزة حول المجال يمارس عادة عيادة بيطرية مستشفى بيطري المزرعة للطب دور كبير حماية البشر الأمراض التي تنتقل عن طريق الأكل أصبح التخصص شائعاً السنوات الأخيرة ومن تلك التخصصات: التخدير علم السلوك الجلدية الحالات الطارئة والعناية الحثيثة الباطني امراض القلب السرطان العيون الأعصاب المشتركة المعدية التناسليات والولادة التصوير الشعاعي والجراحة
كتاب
Femtomolar bradykinin-induced relaxation of isolated bovine coronary arteries, mediated by endothelium-derived nitric oxide
كتاب
Femtomolar bradykinin-induced relaxation of isolated bovine coronary arteries, mediated by endothelium-derived nitric oxide
Femtomolar bradykinininduced relaxation of isolated bovine coronary arteries, mediated by endotheliumderived nitric oxide من كتب طب بيطرى
We reported previously that bradykinin induces endothelium-dependent relaxation at nanomolar (nM) concentrations in isolated bovine coronary arteries with an intact endothelium. Recently we have found that in the presence of 10 microM indomethacin, femtomolar (fM) concentrations of bradykinin induce endothelium-dependent relaxation in some bovine coronary arteries (approximately 10% of the coronary arteries examined). The present study was designed to characterize the relaxation induced by fM bradykinin. Relaxation was completely abolished by repeated application of fM bradykinin, by 100 microM N(omega)-nitro-L-arginine methyl ester and by 10 microM methylene blue. Relaxation induced by nM bradykinin was partly affected by these treatments. Relaxation induced by both concentrations of bradykinin was inhibited by a B2-kinin receptor antagonist, [Thi5,8, D-Phe7]-bradykinin, in a concentration-dependent manner, but not by a B1-kinin receptor antagonist, des-Arg9, [Leu8]-bradykinin. In the presence of 10 microM captopril, an angiotensin-converting enzyme (ACE) inhibitor, all coronary arteries examined in this experiment showed endothelium-dependent relaxation to fM bradykinin. These results show that some bovine coronary arteries relax in response to fM bradykinin, and this response is mediated predominantly by the release of nitric oxide via stimulation of endothelial B2-kinin receptors. The relaxation may be dependent on ACE activity.
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