📘 ❞ DNA Topoisomerase Protocols ❝ كتاب ــ Mary-Ann Bjornsti and Neil Osheroff اصدار 1999
Biology Books - 📖 ❞ كتاب DNA Topoisomerase Protocols ❝ ــ Mary-Ann Bjornsti and Neil Osheroff 📖
█ _ Mary Ann Bjornsti and Neil Osheroff 1999 حصريا كتاب DNA Topoisomerase Protocols 2024 Protocols: نبذه عن الكتاب: The helical structure of duplex allows for the faithful duplication and transmission genetic information from one generation to next, at the same time maintaining integrity polynucleotide chains The complementary nature two antiparallel strands enables each serve as a template synthesis respective daughter intertwining these in further ensures the integrity helix by physically linking individual a structure stabilized hydrogen bonding and stacking interactions between the hydrophobic bases However, same features pose a number topological constraints that affect most processes involving DNA, such DNA replication, transcription, nucleosome assembly (reviewed [1–4]) During semiconservative replication, example, progressive unwinding template requires swivel alleviate overwinding ahead moving replication fork Of course, apparatus may simply follow path DNA template this soon leads second problem how to unlink interwound helices following completion This decatenation molecules is absolutely required case of circular genomes plasmids, which are physically linked circles Similar considerations apply process transcription, where movement transcription complex along may also produce local unwinding behind the DNA be viewed Biology Books مجاناً PDF اونلاين Biologically Biology natural science concerned with study life, its various forms function, organisms interact other surrounding environment word biology Greek made up words: bio (βίος) meaning life And loggia ( λογία) means or Biology: similarity vegetation animal cover on edges African American states, existence fossil Branches biology Biology an ancient thousands years old modern began nineteenth century has multiple branches Among them are: Anatomy Botany Biochemia Biogeography Biofisia Cytology cell science Ecology environmental science Development Embryology embryology Genetics genetics Histology histology Anthropology anthropology Microbiology bacteriology Molecular Biology Physiology functions organs Taxonemia taxonomy Virology virology Zoology zoology
كتاب
DNA Topoisomerase Protocols
ــ Mary-Ann Bjornsti and Neil Osheroff
صدر 1999م
كتاب
DNA Topoisomerase Protocols
ــ Mary-Ann Bjornsti and Neil Osheroff
صدر 1999منبذه عن الكتاب:
The helical structure of duplex DNA allows for the faithful duplication and
transmission of genetic information from one generation to the next, at the
same time maintaining the integrity of the polynucleotide chains. The complementary nature of the two antiparallel DNA strands enables each to serve as a
template for the synthesis of the respective daughter DNA strands. The intertwining of these polynucleotide chains in duplex DNA further ensures the
integrity of the DNA helix by physically linking the individual strands in a
structure stabilized by hydrogen bonding and stacking interactions between
the hydrophobic bases. However, these same features pose a number of topological constraints that affect most processes involving DNA, such as DNA
replication, transcription, and nucleosome assembly (reviewed in [1–4]).
During semiconservative DNA replication, for example, the progressive
unwinding of the DNA template requires a swivel in the DNA duplex to alleviate the overwinding of the strands ahead of the moving replication fork. Of
course, the replication apparatus may simply follow the helical path of the DNA
template strands. However, this soon leads to a second problem of how to
unlink the interwound DNA helices following the completion of DNA synthesis. This decatenation of daughter molecules is absolutely required in the case
of circular genomes and plasmids, in which the template strands are physically
linked circles. Similar considerations apply to the process of transcription,
where the movement of a transcription complex along the DNA template may
also produce a local unwinding of the DNA behind and overwinding of the
DNA ahead. This may be viewed
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