📘 ❞ Functional Genomics Methods and Protocols-Humana Press ❝ كتاب ــ Michael J. Brownstein Arkady B. Khodursky اصدار 2003
كتب الطب البشري - 📖 ❞ كتاب Functional Genomics Methods and Protocols-Humana Press ❝ ــ Michael J. Brownstein Arkady B. Khodursky 📖
█ _ Michael J Brownstein Arkady B Khodursky 2003 حصريا كتاب Functional Genomics Methods and Protocols Humana Press 2024 Press: Dramatic technological advances have marked every quantum leap in our understanding of biological systems Advances manipulating sequencing DNA triggered the last such More than 20 years ago this technology began finding its way into biology laboratories, multiple landmark discoveries followed, including genomes several prokaryotic eukaryotic species This, turn, spawned a new interest in bioinformatics, structural biology, high throughput methods that would allow scientists to look at response entire genome physiological, pharmacological, pathological changes Whether transition was driven by exhaustion existing hypothesis pool, subconscious adoption the old “new paradigm” complexity, or an instinctual urge among biologists for interesting phenomena is not really important What are becoming more and more routine available, experimentalists theoreticians must be prepared take advantage them Spotted microarrays fall category They power functional genomics, nascent research field dealing with the structure activity global relationships between genotype phenotype The birth can traced back three seminal papers (2,3,12) These works grew from realization by placing individual sequence elements on solid surface one probe hybridization nearly unlimited number targets simultaneously Since then, similar ad infinitum approaches been used monitor relative protein levels (6), protein functions (15), cellular activities (16), molecular interactions (10) These breakthrough studies will set stage development fields of proteomics, metabolomics, etc However, moment only functional genomic techniques surfaces enjoy relatively wide acceptance because they based sounder physical chemical principles كتب الطب البشري مجاناً PDF اونلاين هو من أكثر التخصصات التي تفيد المجتمع وأكثرها تواصلاً معه يشارك الطبيب العديد الحملات الصحية التثقيفية والمشاركة البرامج الوقائية وحماية البيئة واستخدام كل وسيلة فعَّآلة لتحقيق ذلك ويساهم أيضاً رفع مستوى الوعي الصحي وتقديم المشورة للمجتمع يحتوي هذا القسم علي مجموعة الكتب المتميزة تشمل: الإلمام الكامل بالأمراض تصيب جسم الإنسان والأعراض المصاحبة لهذه الأمراض وطرق تطوير صحة ويتخصص المجال أطباء يحصلون شهادة MD وهي أول الشهادات يحصل عليها المبتدأ مجال الطب
كتاب
Functional Genomics Methods and Protocols-Humana Press
ــ Michael J. Brownstein Arkady B. Khodursky
صدر 2003م
كتاب
Functional Genomics Methods and Protocols-Humana Press
ــ Michael J. Brownstein Arkady B. Khodursky
صدر 2003م-
مساهمة من: esraa
( الخميس 23 يناير 2020 ( 4:06 مساءً )) - تبليغ عن سوء استخدام
Dramatic technological advances have marked every quantum leap in our
understanding of biological systems. Advances in manipulating and sequencing DNA triggered the last such leap. More than 20 years ago this technology
began finding its way into biology laboratories, and multiple landmark discoveries have followed, including the sequencing of the genomes of several
prokaryotic and eukaryotic species. This, in turn, spawned a new interest in
bioinformatics, structural biology, and high-throughput methods that would
allow scientists to look at the response of the entire genome to physiological,
pharmacological, and pathological changes. Whether this transition was driven
by exhaustion of the existing hypothesis pool, a subconscious adoption of the
old “new paradigm” of biological complexity, or an instinctual urge among
biologists to look for new and interesting phenomena is not really important.
What is important is that high-throughput methods are becoming more and
more routine and available, and experimentalists and theoreticians must be prepared to take advantage of them. Spotted DNA microarrays fall into this category. They power functional genomics, a nascent research field dealing with
the structure and activity of genomes and global relationships between genotype and phenotype. The birth of the field can be traced back to three seminal
papers (2,3,12). These three works grew from the realization that by placing
individual sequence elements on a solid surface one can probe by hybridization a nearly unlimited number of targets simultaneously. Since then, similar
ad infinitum approaches have been used to monitor relative protein levels (6),
protein functions (15), cellular activities (16), and molecular interactions (10).
These breakthrough studies will set the stage for the development of the fields
of functional proteomics, metabolomics, etc. However, at the moment only
functional genomic techniques on solid surfaces enjoy relatively wide acceptance because they are based on sounder physical-chemical principles.
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