📘 ❞ Biopolymer Methods in Tissue Engineering-Humana Press ❝ كتاب ــ Anthony P. Hollander Paul V. Hatton اصدار 2003
Biology Books - 📖 كتاب ❞ Biopolymer Methods in Tissue Engineering-Humana Press ❝ ــ Anthony P. Hollander Paul V. Hatton 📖
█ _ Anthony P Hollander Paul V Hatton 2003 حصريا كتاب ❞ Biopolymer Methods in Tissue Engineering Humana Press ❝ 2024 Press: نبذه عن الكتاب: 1 1 Absorbable Poly α Hydroxy Acids Poly (α hydroxyacids) were found to be bioabsorble and biocompatible in the 1960s (1,2) They are the most widely known, studied used bioabsorbable synthetic polymers medicine Polyglycolide (PGA) poly L lactide (PLLA) homopolymers their copolymers (PLGA), as well polylactic acid stereocopolymers produced using , D or DL lactides rasemic polymer copolymer PLDLA all (3) hydroxy acids) can polymerized via condensation, although only low mol wt In order obtain a higher thus mechanical strength longer absorption time, from the cyclic dimers ring opening polymerization appropriate initiators and co The commonly initiator is stannous octoate (2,3) The rate both vitro vivo of hydroxy acids) is dependent on microstructural, macrostructural, environmental factors listed Table degradation mechanism mainly hydrolysis Polylactides (PLAs) absorb bulk erosion—e g erosion occurs simultaneously throughout device Some studies have revealed an autocatalytic PLAs Autocatalysis shows more dense surface layer faster degradation inside samples which has also been reported for PLLA (7), (8), fiber reinforced 70 30 (9), for PDLLA (10), PLA50 (11) Li et al proposed degradation model with faster degrading core slowly shell Biology Books مجاناً PDF اونلاين Biologically Biology natural science that concerned study life, its various forms function, how these organisms interact each other surrounding environment word biology Greek made up two words: bio (βίος) meaning life And loggia ( λογία) means Biology: similarity vegetation animal cover edges African American states, existence same fossil Branches biology Biology ancient thousands years old modern began nineteenth century This multiple branches Among them are: Anatomy Botany Biochemia Biogeography Biofisia Cytology cell science Ecology science Development Embryology embryology Genetics genetics Histology histology Anthropology anthropology Microbiology bacteriology Molecular Biology Physiology functions organs Taxonemia taxonomy Virology virology Zoology zoology
كتاب
Biopolymer Methods in Tissue Engineering-Humana Press
ــ Anthony P. Hollander Paul V. Hatton
صدر 2003م
كتاب
Biopolymer Methods in Tissue Engineering-Humana Press
ــ Anthony P. Hollander Paul V. Hatton
صدر 2003منبذه عن الكتاب:
1.1. Absorbable Poly-α-Hydroxy Acids
Poly (α-hydroxyacids) were found to be bioabsorble and biocompatible in
the 1960s (1,2). They are the most widely known, studied and used bioabsorbable synthetic polymers in medicine. Polyglycolide (PGA) and poly-L-lactide
(PLLA) homopolymers and their copolymers (PLGA), as well as polylactic
acid stereocopolymers produced using L-, D-, or DL-lactides and rasemic polymer copolymer PLDLA are all poly (α-hydroxyacids) (3). Poly (α-hydroxy
acids) can be polymerized via condensation, although only low mol-wt polymers are produced. In order to obtain a higher mol wt and thus mechanical
strength and longer absorption time, the polymers are polymerized from the
cyclic dimers via ring-opening polymerization using appropriate initiators and
co-initiators. The most commonly used initiator is stannous octoate (2,3).
The absorption rate both in vitro and in vivo of the poly (α-hydroxy acids) is
dependent on the microstructural, macrostructural, and environmental factors
listed in Table 1. The degradation mechanism is mainly hydrolysis. Polylactides (PLAs) absorb via bulk erosion—e.g., erosion occurs simultaneously
throughout the device. Some studies have revealed an autocatalytic degradation of PLAs. Autocatalysis shows as a more dense surface layer and as faster
degradation inside the samples which has also been reported for as-polymerized PLLA (7), for PLLA (8), for PLLA-fiber-reinforced PLDLA 70/30 (9), for
PDLLA (10), and for PLA50 samples (11). Li et al. have proposed a degradation
model for PLA50 with a faster degrading core and a more slowly degrading shell
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